Jurí C, Chana P, Kramer V, Pruzzo P, Amaral H, Riss P, Rösch F.
Imaging Nigrostriatal Dopaminergic Deficit in Holmes Tremor with 18F-PR04.MZ-PET/CT
Clinical Nuclear Medicine 2015, in press
Reibel AT1, Müller SS, Pektor S, Bausbacher N, Miederer M, Frey H, Rösch F.
Fate of linear and branched polyether-lipids in vivo in comparison to their liposomal formulations by 18F-radiolabeling and positron emission tomography.
Biomacromolecules. 2015 Mar 9;16(3):842-51. doi: 10.1021
Schieferstein H, Piel M, Beyerlein F, Lüddens H, Bausbacher N, Buchholz HG, Ross TL, Rösch F.
Selective binding to monoamine oxidase A: in vitro and in vivo evaluation of 18F-labeled β-carboline derivatives.
Bioorg Med Chem. 2015 Feb 1;23(3):612-23. doi: 10.1016
Habermeier A1, Graf J, Sandhöfer BF, Boissel JP, Rösch F, Closs EI.
System L amino acid transporter LAT1 accumulates O-(2-fluoroethyl)-L-tyrosine (FET).
Amino Acids February 2015, Volume 47, Issue 2, pp 335-344
Piel M, Vernaleken I , Rösch F.
Positron Emission Tomography in CNS drug discovery and drug monitoring
J. Med. Chem., 2014, 57 (22), pp 9232–9258
Piel M, Schmitt U, Bausbacher N, Buchholz HG, Gründer G, Hiemke C, Rösch F.
Evaluation of P-glycoprotein (abcb1a/b) modulation of [18F]fallypride in MicroPET imaging studies
Neuropharmacology Volume 84, September 2014, Pages 152–158
Beyerlein F, Piel M, Höhnemann S, Rösch F.
Automated synthesis and purification of [18F]fluoro-[di-deutero]methyl tosylate
J. Label Compd. Radiopharm 2013, 56 360-363
Riss JP, Höhnemann S, Piel M, Rösch F.
Two-step radiosynthesis of [18F]FE-β-CIT and [18F]PR04.MZ
J. Label Compds. Radiopharm 2013, 56 356-359
Riss PJ, Stockhofe K, Rösch F.
Tropane derived 11C and 18F-labelled DAT ligands
J Lab. Compds. Radiopharm. 56 (2013) 149-158.
DOI: 10.1002/jclr.3018
Cumming P, Xiong G. LaFougere C, Rominger A, Bartenstein P, Buchholz H-G, Piel M, Rösch F, Gründer G, Vernaleken I.
Surrogate markers for cerebral blood flow correlate with [18F]-fallypride binding potential at dopamine D2/3 receptors in human striatum.
Synapse 67/4 (2013) 199-203
10.1002/syn.21630.
Herth MH, Kramer V, Gillings N, Rösch F, Knudsen GM.
Direct radiofluorination of [18F]MH.MZ for 5-HT2A receptor molecular imaging with PET.
J Label Compd Radiopharm 55 (2012) 354-558.
Allmeroth M, Moderegger D, Biesalski B, Koynov K, Rösch F, Thews O, Zentel R.
Modifying the body distribution of HPMA-based copolymers by molecular weight and aggregate formation.
Biomacromolecules. 12(7) (2011) 2841-9.
Hemmelmann M, Knoth C, Schmitt U, Allmeroth M, Moderegger D, Barz M, Koynov K, Hiemke C, Rösch F, Zentel R.
HPMA based amphiphilic copolymers mediate central nervous effects of domperidone.
Macromol Rapid Commun. 32/9-10 (2011) 712-717
Spreckelmeyer KN, Paulzen M, Raptis M, Baltus T, Schaffrath S, Van Waesberghe J, Zalewski MM, Rösch F, Vernaleken I, Schäfer WM, Gründer G.
Opiate-induced dopamine release is modulated by severity of alcohol dependence: An [18F]fallypride PET study.
Biol Psychiatry 70 (2011) 770-776
Vernaleken I, Peters L, Raptis M, Lin R, Buchholz H-G, Zhou Yun, Winz O, Rösch F, Bartenstein P, Wong D, Schaefer W, Gründer G.
The applicability of SRTM in [18F]Fallypride PET investigations: Impact of scan durations.
JCBFM 31 (2011) 1958–1966
Schmitt U, Lee DE, Herth MM, Piel M, Buchholz H-G, Rösch F, Hiemke C, Lueddens H, Debus F.
P-Glycoprotein influence on the brain uptake of a 5-HT 2A ligand: [18F]MH.MZ.
Neuropsychobiology 63 (2011) 183–190.
Bauman A, Piel M, Höhnemann S, Krauss A, Jansen M, Solbach C, Dannhardt G, Rösch F.
Synthesis, labelling and evaluation of hydantoin-substituted indole carboxylic acids as potential ligands for PET-Imaging of the glycine binding site of the NMDA-receptor.
J Labell Compds Radiopharm 54 (2011) 645-656
P.J. Riss, M. Piel, V. Bockhart, N. Bausbacher, H.-G. Buchholz, H. Lueddens, F. Rösch.
The DAT ligand [18F]PR17.MZ mirrors the in vivo pharmacokinetic profile of [11C]cocaine with significantly improved monoamine transporter selectivity
ChemMedChem. 5/10 (2010) 1686-8
V. Kramer, M.M. Herth, M.A. Santini, M. Palner, G.M. Knudsen, F. Rösch.
Structural combination of established 5-HT receptor ligands: New aspects of the binding mode
Chem Biol Drug Des. 76(4) (2010) 361-6
E. Hühn, H.-G. Buchholz, G. Shazly, S. Maus, O. Thews, N. Bausbacher, F. Rösch, M. Schreckenberger, P. Langguth.
Predicting the in vivo release from a liposomal formulation by IVIVC and non-invasive positron emission tomography imaging
Eur J Pharm Sci. 41/1 (2010) 71-77
I. Vernaleken, H. Janouschek, M. Raptis, S. Hellmann, T. Veselinovic, A. Bröcheler, C. Boy, P. Cumming, C. Hiemke, F. Rösch,
W.M. Schäfer, G. Gründer.
Dopamine D2/3 receptor occupancy by quetiapine in striatal and extrastriatal areas
Int J Neuropsychopharmacol. 13/7 (2010) 951-960
F. Debus, M.M. Herth, M. Piel, H.-G. Buchholz, N. Bausbacher, V. Kramer, H. Lüddens, F. Rösch.
18F-labeling and evaluation of novel MDL 100907 derivatives as potential 5-HT2A antagonists for molecular imaging
Nucl Med Biol. 37(4) (2010) 487-95
G. Nikisch, P. Baumann, B. Kießling, M. Reinert, G. Wiedemann, J. Kehr, A.A. Mathé, M. Piel, F. Rösch, H. Weisser, P. Schneider,
A. Hertel.
Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first - episode schizophrenia treated with quetiapine
J Psychiatr Res 44/12 (2010) 754-9
P.J. Riss, F. Rösch.
Effective microwave-assisted direct radiosynthesis of [18F]PR04.MZ, and [18F]LBT999: Selective dopamine transporter ligands for qunatitative molecular imaging by means of PET
Bioorg Med Chem 17 (2009) 7630-4
Herth MM, Kramer V, Rösch F.
Synthesis of novel WAY 100635 derivatives containing a norbornene group and radiofluoroination of
[18F]AH1.MZ, as a Serotonin 5-HT1A receptor antagonist for molecular imaging.
J Label Compd Radiopharm 52/6 (2009) 201-207
P.J. Riss, V. Soskic, A. Schrattenholz, F. Rösch.
Synthesis and radiosynthesis of N5-[18F]fluoroethyl-pirenzepine and its metabolite N5-[18F]fluoroethyl-LS 75
J Label Compd Radiopharm 52 (2009) 576-9
P.J. Riss, F. Debus, R. Hummerich, U. Schmidt, P. Schloss, H. Lüddens, F. Rösch.
Ex vivo and in vivo evaluation of [18F]PR04.MZ in rodents: a selective dopamine transporter imaging agent
ChemMedChem 4 (2009) 1480-7
M.M. Herth, M. Barz, D. Moderegger, M. Allmeroth, M. Jahn, O. Thews, R. Zentel, F. Rösch
Radioactive labeling of defined HPMA-based polymeric structures using [18F]FETos for in vivo imaging by Positron Emission Tomography
Biomacromolecules 10 (2009) 1697-1703
M.M. Herth, M. Piel, F. Debus, U. Schmitt, H. Lüddens, F. Rösch.
Preliminary in vivo and ex vivo evaluation of the 5-HT2A imaging probe [18F]MH.MZ
Nucl Med Biol 36(4) (2009) 447-54
M.M. Herth, V. Kramer, M. Piel, M. Palner, P.J. Riss, G.M. Knudsen, F. Rösch.
Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging
with PET.
Bioorg Med Chem. 17(8) (2009) 2989-3002.
I. Vernaleken, C. Fellows, H. Janouschek, A. Bröcheler, T. Veselinovic, C. Landvogt, C. Boy, H.-G. Buchholz, K. Spreckelmeyer,
P. Bartenstein, P. Cumming, C. Hiemke, F. Rösch, W. Schäfer, DF. Wong, G. Gründer.
Striatal and extrastriatal D2/D3-receptor-binding properties of ziprasidone: a positron emission tomography study with [18F]Fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone)
J Clin Psychopharmacol 28 (2008) 608-617
P.J. Riss, F. Rösch.
A convenient chemo-enzymatic of trans-1-toluenesulfonyloxymethyl-2-fluoromethyl-cyclopropane
Org Biomol Chem. 6 (2008) 4567–4574
T. Kienast, T. Siessmeier, J. Wrase, D.F. Braus, MN. Smolka, H.-G. Buchholz, M. Rapp, M. Schreckenberger, F. Rösch, P. Cumming,
G. Gruender, K. Mann, P. Bartenstein, A. Heinz.
Ratio of dopamine synthesis capacity to D2 receptor availability in ventral striatum correlates with central processing of affective stimuli
Eur J Nucl Med Mol Imaging 35 (2008) 1147-1158
M.M. Herth, F. Debus, M. Piel, M. Palner, G.M. Knudsen, H. Lüddens, F. Rösch.
Total synthesis and evaluation of [18F]MH.MZ.
Bioorg Med Chem Lett. 18(4) (2008) 1515-1519
I. Vernaleken, C. Fellows, H. Janouschek, A. Bröcheler, T. Veselinovic, C. Landvogt, C.Boy, H.-G. Buchholz, P. Bartenstein, P. Cumming, C. Hiemke, F. Rösch, W. Schäfer, DF. Wong, G. Gründer.
Striatal and extrastriatal D2/3 receptor binding properties of Ziprasidone: a PET study with [18F]Fallypride
J Clin Psychopharmacol 28(6) (2008) 608-17
G. Gründer, C. Fellows, H. Janouschek, T. Veselinovic, C. Boy, A. Bröcheler, K.M. Kirschbaum, S. Hellmann, K.M. Spreckelmeyer,
C. Hiemke, F. Rösch, W.M. Schaefer, I. Vernaleken.
Brain and plasma pharmacokinetics of Aripiprazole in patients with Schizophrenia: An [18F]Fallypride PET study
Am J Psychiatry 165 (2008) 988-985
C. Fehr, I. Yakushev, N. Hohmann, H.-G. Buchholz, C. Landvogt, H. Deckers, A. Eberhardt, M. Kläger, MN. Smolka, A. Scheurich,
T. Dielentheis, L.G. Schmidt, F. Rösch, P. Bartenstein, G. Gründer, M. Schreckenberger.
Association of low striatal dopamine D2 receptor availability with nicotine dependence similar to that seen with other drugs of abuse
Am J Psychiatry 165 (2008) 507-515.
M. Piel, A. Bauman, R.P. Baum, S. Höhnemann, I. Klette, R. Wortmann, F. Rösch.
Improved automated synthesis of [18F]fluoroethylcholine as a radiotracer for cancer imaging
Bioorg Med Chem 15 (2007) 3171-3175
D. Stark, M. Piel, H. Hübner, P. Gmeiner, G. Gründer, F. Rösch.
In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D2-like dopamine receptors
Bioorg Med Chem 15 (2007) 6819-6829
I. Vernaleken, C. Weibrich, T. Siessmeier, H.-G. Buchholz, F. Rösch, A. Heinz, P. Cumming, P. Stoeter, P. Bartenstein, G. Gründer.
Asymmetry in dopamine D2/3 receptors of NC is lost with age
Neuroimmage 34 / 3 (2007) 870-878.
T. Siessmeier, T. Kienast, J. Wrase, J.L. Larsen, D.F. Braus, MN. Smolka, H.-G. Buchholz, M. Schreckenberger, M. Rösch, P. Cumming,
K. Mann, P. Bartenstein, A. Heinz.
Antiamphiphysin-positive stiff-person syndrome associated with small cell lung cancer
Mov Disord. 21 (2006) 1285-1287
G. Gründer, C. Landvogt, I. Vernaleken, H.-G. Buchholz, J. Ondracek, T. Siessmeier, S. Hartter, M. Schreckenberger, P. Stoeter,
C. Hiemke, F. Rösch, DF. Wong, P. Bartenstein.
The striatal and extrastriatal D2/D3 receptor-binding profile of clozapine in patients with schizophrenia
Neuropsychopharmacology 31(5) (2006) 1027-35
T. Siessmeier, T. Kienast, J. Wrase, J.L. Larsen, D.F. Braus, MN. Smolka, H.-G. Buchholz, M. Schreckenberger, F. Rösch, P. Cumming,
K. Mann, P. Bartenstein, A. Heinz.
Net influx of plasma 6-[18F]fluoro-L-DOPA (FDOPA) to the ventral striatum correlates with prefrontal processing of affective stimuli
Eur J Neurosci 24(1) (2006) 305-13
A. Bartoli, N. Belcari, D. Stark, S. Höhnemann, M. Piel, M. Jennewein, U. Schmitt, J. Tillmanns, O. Thews, Ch. Hiemke, F. Rösch,
A. Del Guerra.
Preliminary assessment of the imaging capability of the YAP-(S)PET small animal scanner in neuroscience
Nucl Instr Methods A 569 (2006) 488-491
K.J. Werhahn, C.H. Landvogt, S. Klimpe, H.-G. Buchholz, W. Müller-Forell, I. Yakushev, M. Piel, F. Rösch, M. Schreckenberger,
P. Bartenstein.
Decreased temporal dopamine D2/D3 receptor binding in temporal lobe epilepsy: an 18F-Fallypride PET study
Epilepsia 47 (2006) 1392-1396
U. Baumgärtner, H.-G. Buchholz, A. Bellosevich, W. Magerl, T. Siessmeier, R. Rolke, S. Höhnemann, M. Piel, F. Rösch, H.-J. Wester,
G. Henriksen, P. Stoeter, P. Bartenstein, R.-D. Treede, M. Schreckenberger.
High opiate receptor binding potential in the human lateral pain system
Neuroimage 30 (2006) 692-699
A. Heinz, T. Siessmeier, J. Wrase, H.-G. Buchholz, G. Gründer, Y. Kumakura, P. Cumming, M. Schreckenberger, MN. Smolka, F. Rösch,
K. Mann, P. Bartenstein.
Correlation of alcohol craving with striatal dopamine synthesis capacity and D2/3 receptor availability: A combined [18F]DOPA and [18F]DMFP PET study in detoxified alcoholic patients
Am J Psychiatry 8 (2005) 1515-20
A. Helisch, E. Schirrmacher, O. Thews, R. Schirrmacher, H.-G. Buchholz, W. Dillenburg, S. Höhnemann, J. Tillmanns, I. Wessler, R. Buhl, F. Rösch, P. Bartenstein.
Demonstration of pulmonary beta(2)-adrenergic receptor binding in vivo with [18F]fluoroethyl-fenoterol in a guinea pig model
Eur J Nucl Med Mol Imaging 32 (2005) 1324-1328
S. Schneider, P.J. Feilen, M. Schreckenberger, M. Schwanstecher, C. Schwanstecher, H.-G. Buchholz, O. Thews, K. Oberholzer,
A. Korobeynikov, A. Bauman, S. Comagic, M. Piel, E. Schirrmacher, CY. Shiue, AA. Alavi, P. Bartenstein, F. Rösch, M.M. Weber,
H.H. Klein, R. Schirrmacher.
In vitro and in vivo evaluation of novel glibenclamide derivatives as imaging agents for the non-invasive assessment of the pancreatic islet cell mass in animals and humans
Exp Clin Endocrinol Diabetes 7 (2005) 388-395
T. Siessmeier, Yun Zhou, H.-G. Buchholz, C.H. Landvogt, I. Vernaleken, M. Piel, R. Schirrmacher, F. Rösch, M. Schreckenberger,
D-F. Wong, P. Cumming, G. Gründer, P. Bartenstein.
Parametric mapping of the binding in human brain of D2-receptor ligands of different affinities
J Nucl Med 6 (2005) 964-97
A. Heinz, T. Siessmeier, J. Wrase, D. Hermann, S. Klein, S.M. Grüsser-Sinopoli, H. Flor, D.F. Braus, H.-G. Buchholz, G. Gründer,
M. Schreckenberger, M. Smolka, F. Rösch, K. Mann, P. Bartenstein.
Correlation between dopamine D2 receptors in the ventral striatum and central processing of alcohol cues and craving
Am J Psychiatry 161 (2004) 1783-1789
M. Schreckenberger, S. Hägele, T. Siessmeier, H-G. Buchholz, H. Armbrust-Henrich, F. Rösch, G. Gründer, P. Bartenstein, T. Vogt.
The dopamine D2-like receptor ligand 18F-Desmethoxyfallypride: An appropriate fluorinated PET tracer for the differential
diagnosis of Parkinsonism.
Eur J Nucl Med Mol Imaging 8
(2004) 1128-1135
I. Vernaleken, T. Siessmeier, H.-G. Buchholz, S. Härtter, Ch. Hiemke, P. Stoeter, F. Rösch, P. Bartenstein, G. Gründer.
High striatal occupancy of D2-like dopamine receptors by amisulpride in brain of schizophrenic patients: implications for atypical antipsychotic mechanism of action.
Int J Neuropsychopharmacol 7/4 (2004) 421-430
G. Gründer, C. Landvogt, I. Vernaleken, H-G. Buchholz, J. Ondracek, T. Siessmeier, S. Härtter, P. Stoeter, O. Rousset, D. F. Wong,
Ch. Hiemke, F. Rösch, P. Bartenstein.
The straital and extrastriatal D2 dopamine receptor binding profile of clozapine in patients with schizophrenia
(2004) submitted.
I. Vernaleken, T. Siessmeier, H-G. Buchholz, P. Stoeter, F. Rösch, P. Bartenstein, G. Gründer
Assymetry in caudate nucleus D2-like dopamine receptors is lost with age: A 18F-Desmethoxyfallypride study in healthy volunteers.
(2004) submitted.
M. Schreckenberger, S. Hägele, T. Siessmeier, H.-G. Buchholz, H. Armbrust-Henrich, F. Rösch, G. Gründer, P. Bartenstein, T. Vogt.
The dopamine D2-like receptor ligand 18F-Desmethoxyfallypride: An appropriate fluorinated PET tracer for the differential diagnosis
of Parkinsonism.
Eur J Nucl Med Mol Imaging 8 (2004) 1128-1135.
B. Wängler, S. Schneider, O. Thews, E. Schirrmacher, S. Comagic, P. Feilen, C. Schwanstecher, M. Schwanstecher, C-Y. Shiue,
A. Alavi, S. Höhnemann, M. Piel, F. Rösch, R. Schirrmacher.
Synthesis and evaluation of (S)-2-(2-[18F]fluoroethoxy)-4-([3-methyl-1-(2-piperidin-1-yl-phenyl)- butyl-carbamoyl]-methyl)-benzoic acid ([18F]repaglinide): a promising radioligand for quantification of pancreatic beta-cell mass with positron emission tomography (PET).
Nucl Med Biol 31 (2004) 639-647
S. Schneider, E. Schirrmacher, M. Schreckenberger, M. Schwanstecher, C. Schwanstecher, P. Feilen, H. Bucholz, O. Thews,
K. Oberholzer, C-Y. Shiue, AA. Alavi, F. Rösch, M. Weber, R. Schirrmacher.
In vitro and in vivo evaluation of novel fluorinated glibenclamide derivatives as imaging agents for the non-invasive assessment of the pancreatic islet cell mass in animals and humans.
Diabetologica 2004, submitted
A. Heinz, T. Siessmeier, J. Wrase, D. Hermann, S. Klein, SM. Grüsser-Sinopoli , H. Flor , DF. Braus, H.-G. Buchholz, G. Gründer,
M. Scheckenberger, M. Smolka, F. Rösch, K. Mann, P. Bartenstein.
Correlation between dopamin D2 receptors in the ventral striatum and central processing of alcohol cues and craving.
Am J Psychiatry 161 (2004) 1783-1789
M. Piel, R. Schirrmacher, S. Höhnemann, W. Hamkens, B. Kohl, M. Jansen, U. Schmitt, H. Lüddens, G. Dannhardt, F. Rösch.
Synthesis and evaluation of 5,7-dichloro-4-(3-{4-[4-(2-[18F]fluoroethyl)-piperazin-1-yl]-phenyl}-ureido)-1,2,3,4-tetrahydroquinoline -2-carboxylic acid as a potential NMDA ligand to study glutamergic neurotransmission in vivo.
J Label Compd Radiopharm, 46 (2003) 645-659
E. Schirrmacher, R. Schirrmacher, A. Helisch, W. Dillenburg, O. Thews, I. Wessler, R. Buhl, S. Höhnemann, HG. Buchholz, P. Bartenstein, HJ. Machulla, F. Rösch.
Synthesis and preliminary evaluation of (R,R) (S,S) -(2-(2-[4-(2-[F-18]fluoroethoxy)phenyl]-1-methylamino)-1-hydroxyethyl)benzene-1,3-diol ([F-18]FEFE) for the in vivo visualisation and quantification of the β2-adrenergic receptor status in lung.
Biomed Chem Lett, 13/16 (2003) 2687-2692
A. Schmitz, C-Y. Shiue, Q. Feng, GG. Shiue, S. Deng, MT. Pourdehnad, R. Schirrmacher, M. Vatamaniuk, N. Doliba, F. Matschinsky,
B. Wolf, F. Rösch, A. Naji, AA. Alavi.
Synthesis and evaluation of fluorine-18 labeled glyburide analogs as beta-cell imaging agents.
Nucl Med Biol, 31 (2004) 483-491
Bauman A, Piel M, Schirrmacher R, Rösch F.
Efficient alkali iodide promoted 18F-fluoroethylations with 2-[18F]fluoroethyl tosylate and 1-bromo-2-[18F]fluoroethane.
Tetrahedron Letters 44 (2003) 9165-9167
G. Gründer, T. Siessmeier, M. Piel, I. Vernaleken, H-G. Buchholz, Yun Zhou, Ch. Hiemke, D. Wong, F. Rösch, P. Bartenstein.
Quantification of D2-like dopamine receptors in the human brain with [18F]desmethoxyfallypride.
J Nucl Med, 44 (2003) 109-116
R. Schirrmacher, B. Mathiasch, E. Schirrmacher, D. Radnic, F. Rösch.
Syntheses of novel N-([18F]fluoroalkyl)-N-nitroso-4-methyl-benzensulfonamides and decomposition studies of corresponding 19F- and bromo-analogues: Potential new compounds for the 18F-labelling of radiopharmaceuticals.
J Label Compd Radiopharm, 46 (2003) 959-977
R. Schirrmacher, E. Nesseler, W. Hamkens, U. Eichhorn, M. Schreckenberger, B. Kaina, F. Rösch.
An approach to the evaluation of the activity of the DNA repair enzyme O6-methylguanine-DNA-methyl-transferase in tumor tissue in vivo: synthesis of 6-benzyloxy-9-(2-[18F]fluoroethyl)-9H-purin-yl-2-amine.
Appl Radiat Isot, 56 (2002) 511-517
S. Comagic, M. Piel, R. Schirrmacher, S. Höhnemann, F. Rösch.
Efficient synthesis of 2-bromo-1-[18F]fluoroethane and its application in the automated preparation of 18F-fluoroethylated radiopharmaceuticals.
Appl Radiat Isot, 56 (2002) 847-851
R. Schirrmacher, M. Weber, A. Schmitz, C-Y. Shiue, AA. Alavi, P. Feilen, S. Schneider, P. Kann, F. Rösch.
Radiosynthesis of 1-(4-(2-[18F]fluoroethoxy)benzenesulfonyl)-butyl urea: A potential β-cell imaging agent.
J Label Compd Radiopharm, 45 (2002) 763-774
R. Schirrmacher, U. Mühlhausen, B. Wängler, E. Schirrmacher, J. Reinhard, G. Nagel, B. Kaina, M. Piel, M. Wießler, F. Rösch.
Synthesis of 2-amino-6-(2-[18F]fluoro-pyridine-4-ylmethoxy)-9-(octyl-b-D-glycosyl)-purine: A novel radioligand for positron emission tomography studies of the O6-methylguanine-DNA methyltransferase (MGMT) status of tumour tissue.
Tetrahedron Letters, 43 (2002) 6301-6304
R. Schirrmacher, W. Hamkens, M. Piel, U. Schmitt, H. Lüddens, Ch. Hiemke, F. Rösch.
Radiosynthesis and evaluation of (2-((4-(2-[18F]fluoroethoxy)phenyl)bis (4-methoxyphenyl)methoxy)-ethylpiperidine-3-carboxylic acid as a potential GAT-3 ligand to study GABAergig neurotransmission in vivo,
J Label Compd Radiopharm, 44 (2001) 627-642
E. Schirrmacher, R. Schirrmacher, R. Buhl, I. Wessler, H-J. Machulla, F. Rösch.
Synthesis of [18F]fluoroethylfenoterol for imaging β2 receptor status in lung in vivo.
J Label Compd Radiopharm, 44 (2001) 436-438
R. Schirrmacher, G. Shiue, S. J. Shiue, A. Alavi, P. J. Feilen, S. Schneider, J. Beyer, F. Rösch.
Synthesis and first evaluation of new 18F-labelled sulfonylureas for the determination of the beta-cell status in vivo.
J Label Compd Radiopharm, 44 (2001) 418-420
B. Wolf, R. Schirrmacher, GJ. Förster, P. Bartenstein, F. Rösch.
Synthesis and first in vivo-tests of C1-[18F]Ffluoroethylamino asparagine for imaging cancer.
J Label Compd Radiopharm, 44 (2001) 365-367
A. Schildan, R. Schirrmacher, M. Samochocki, C. Christner, A. Maelicke, F. Rösch.
Synthesis and in vitro evaluation of galanthamine derivatives for examination of nicotinic acetylcholine receptor system.
J Label Compd Radiopharm, 44 (2001) 247-249
S. Comagic, M. Piel, R. Schirrmacher, S. Höhnemann, F. Rösch.
Efficient synthesis of 2-bromo-1-[18F]fluoroethane and its application in the automated preparation of 18F-fluoroethylated radiopharmaceuticals.
J Label Compd Radiopharm, 44 (2001) 874-876
G. Gründer, T. Siessmeier, C. Lange-Asschenfeldt, I. Vernaleken, H-G. Buchholz, P. Stoeter, A. Drzezga, H. Lüddens, F. Rösch,
P. Bartenstein.
[18F]fluoroethylflumazenil: a novel tracer for PET imaging of human benzodiazepine receptors.
Eur J Nucl Med, 28 (2001) 1463-1470
W. Hamkens, M. Piel, R. Schirrmacher, U. Schmitt, R. Kleinz, H. Lüddens, G. Gründer, F. Rösch.
Improved synthesis of 5-(2’-[18F]fluoroethyl)flumazenil for in vivo imaging of benzodiazepine receptors.
J Label Compd Radiopharm 42, suppl. 1 (1999) 510-512
R. Schirrmacher, W. Hamkens, M. Piel, J. Brockmann, F. Rösch.
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